Myelodysplastic syndrome, unclassified (MDS-U) This type of MDS is characterized by one or more cytopenia (reduction of mature blood cells), dysplasia (abnormal development of cells) in two or more myeloid cell lines, less than 5% blasts in the bone marrow, and less than 1% blasts in peripheral blood.Ħ. Refractory cytopenia with multilineage dysplasia and ringed sideroblasts (RCMD-RS) Specifically, an individual with RCMD has less than 15% ringed sideroblasts and 5% blasts in the bone marrow.ĥ.
In this condition, at least two types of blood cell (red or white blood cell, and platelet) count are low. Refractory cytopenia with multilineage dysplasia (RCMD) This type usually affects the age group of 50 years old and above and constitutes 30-40% MDS Cases.Ĥ. It is characterized by increased myeloblasts and multilineage dysplasia in the bone marrow and/or peripheral blood. In RAEB, there are too many blasts (up to 19 percent of the cells in the marrow) and not enough red blood cells. Refractory anemia with excess blasts (RAEB) It is characterized by bone marrow erythrodysplasia, ring sideroblasts (iron-loaded mitochondria), and anemia.ģ.
RARS involves a depleted number of red blood cell counts and excessive iron in the red blood cells. This is considered to be an inactive or indolent type of MDS. Refractory anemia with ringed sideroblasts (RARS) Moreover, It is characterized by anemia, mono-lineage dysplasia, dyserythropoiesis, and a low percentage of blasts in the bone marrow and peripheral blood.Ģ. Refractory anemia is a type of MDS that takes place when there are insufficient red blood cells.
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